Formulation and Stability Strategies for Nimodipine: From Particle Engineering to GMP Production

Nimodipine is a dihydropyridine calciumchannel blocker with pronounced cerebrovascular selectivity, used clinically to protect the brain from ischemic injury by preferentially relaxing cerebral arterial smooth muscle while limiting systemic hypotension. Its primary indication is for the prevention and treatment of neurological deficits following aneurysmal subarachnoid haemorrhage (SAH), where nimodipine reduces the risk of delayed cerebral […]